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Those with diabetes or cardiovascular disease are living longer due to better survival rates and better access to kidney treatment, which has resulted in an increased incidence of ESRD in individuals aged 75 or more
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Although the pathophysiology of cisplatin-induced cognitive impairment (CICI) has not been fully elucidated, several pathophysiologic mechanisms, including oxidative stress, inflammation, mitochondrial dysfunction, DNA damage, and apoptosis, have been proposed as possible explanations (Canta et al., 2015
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