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J Plast Reconstr Aesthet Surg 63:11861195
In the study conducted by Secchi et al
Terminal half-life ~2 hours
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(2019) 92:E1899e1911
Recently, through combined application with the CRISPR-Cas9-based base editor, this approach allowed us to characterize individual residues critical for the function of DND1 that is an essential gene in PGC development, 22 in which, a CAG promoter showed to have a high mutagenesis efficiency in vivo
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