Stops mutations Stops molecules inert, preventing their destructive effects Vital for both phase I & phase II liver detoxification Induces normal p53(tumor suppressor) activity by redox modulation, which induces apoptosis in tumor cells Detoxification is another major function
5 The TRIUMPH trial programme TRIUMPH is unusual in pharmaceutical development
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Proposed Mechanisms (Preclinical) Muscle & Satellite-Cell Biology Investigated for effects on muscle satellite cells , including activation, proliferation, and differentiation in response to overload or injury
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