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For example, GLP-1RAs were proven in the clinic to slow the disease progression of Alzheimers disease and Parkinsons disease, attributed in part to their anti-inflammatory and neuroprotective properties [16, 18,19,20,21,22]
Rheumatology 49 , 20102015 (2010)
Significant improvements were observed in comorbidities, including reductions in obstructive sleep apnea ( 30%), hypertension ( 40%), and arthralgia ( 56.5%)
Glutathione plays a role in the optimal functioning of the immune system
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In summary, GLP-1 and GLP-1R show expression in a variety of tissues and the best-studied and most currently clinically relevant effects of GLP-1 is its ability to act as an incretin hormone and reduce appetite, given the global prevalence of T2D and obesity
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