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The melanocortin system and GPCR signalling
doi: 10.1152/ajpendo.00281.2023
5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in white adipose tissue that regulates cellular energy metabolism and fat storage
Fasting Plasma Glucose levels ( 3.30 1.14 mmol/L) and body weight ( 3.87 0.87%) were lowered under treatment with SAR425899
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