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Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N
It works by: Reducing hunger signals Increasing fullness after meals Slowing gastric emptying As calorie intake drops, the body pulls energy from available sources
It also acts as an anti-inflammatory, promoting overall health and well-being
GLP-1s are made naturally by the body and are released after eating, binding to glucagon receptor sites
When food sits longer in your stomach, bacteria in your colon break down undigested carbohydrates and proteins through fermentation