Pay in 4 interest-free payments of $6.00 Learn more
Ships within 48 hours · Estimated delivery Aug 9 - Aug 14
The peptide stimulates both synthesis and breakdown of ECM components while modulating the activity of both metalloproteinases and their inhibitors, creating dynamic matrix remodeling that allows tissue reconstruction without excessive scar formation
This multi-receptor activation enables: GLP-1R activation enhances glucose-dependent insulin secretion and reduces appetite through hypothalamic signaling GIPR activation (highest potency: EC50 0.0643 nM) promotes insulin secretion and modulates lipid metabolism GCGR activation (EC50 5.79 nM) increases energy expenditure and promotes hepatic fat oxidation Combined receptor engagement produces dose-dependent reductions in body weight and improvements in glycemic control Research demonstrates that GLP3s balanced activation across three receptors produces superior metabolic effects compared to single or dual agonists, with phase 2 trials showing up to 24.2% weight reduction in 48 weeks[2]
placebo-controlled study confirmed these effects in real-world use
Sandhu K, Flintoff K, Chatfield MD, Dixon JL, Ramm LE, Ramm GA, Powell LW, Subramaniam VN, Wallace DF
Microbiota dysbiosis controls the neuroinflammatory response after stroke
In a high-quality liposomal liquid, this scent is a marker of potency and purity
