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Large-scale, long-term clinical trials are still lacking to decisively prove anti-aging benefits or prevention of cognitive decline

However, another randomized, double-blind, placebo-controlled trial in 181 patients with diabetic neuropathy found that oral supplementation with either 600 mg/day, 1,200 mg/day, or 1,800 mg/day of lipoic acid for five weeks significantly improved neuropathic symptoms (77)

To test or not to test

Why It Matters for Patients Stronger satiety signals: Patients feel full sooner and may find it easier to stick with smaller meals

Of course, that kind of dose manipulation should only be performed with the informed consent of your doctor