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The analysis revealed that both the comproportionation and triad models were better suited to represent the experimental data than the reduced model, but were inconclusive with respect to overall model selection, given that both AIC/BIC values were extremely similar (Fig
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS
In vitro studies confirm minimal cytotoxicity with no impact on cell viability up to 100 M concentrations across multiple cell types, though higher concentrations may produce non-specific effects that could confound experimental results
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