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10.1016/j.ijbiomac.2019.03.042 Int J Biol Macromol
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These metabolic changes could potentially impact the tumor microenvironment, affecting factors such as nutrient availability and oxidative stress, which are crucial for tumor cell survival and proliferation ( In vitro , SGLT2 exhibited antitumor activity by augmenting caspase 3 cleavage activity and modulating the expression of Bax/Bcl-2 (Figure 3 (Figure 3)
Last reviewed: June 20, 2026 Last updated: June 20, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations