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Publication bias was evaluated visually through funnel plots and formally using Eggers test

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This distinction matters because exogenous GH administration carries a different risk profile than peptide-stimulated endogenous release

The FDA has issued warnings about adverse effects related to improperly compounded GLP-1 RAs as shortages force patients to seek alternative supplies

De Giorgi R, Ghenciulescu A, Yotter C, Taquet M, Koychev I (2025) Glucagon-like peptide-1 receptor agonists for major neurocognitive disorders

According to a Cochrane analysis, although some beneficial effects on pain and improvement in vibration perception threshold have been reported, no conclusive evidence has been found to support a significant reduction in pain after 612 months of treatment with acetyl-L-carnitine in patients with DPN [111]