The headline finding: A systematic review and real-world analysis of 30 clinical studies involving more than 430,000 patients found that metabolic and bariatric surgery consistently exceeded GLP-1 medications across every outcome measured weight loss and obesity-related disease remission alike
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The longer the gap in treatment, the bigger the jump in risk up to a 22% increase for heart attack, stroke and death after two years off GLP-1s, largely erasing the cardiovascular benefits gained during treatment
1% reported fainting, headache, and insomnia