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Redox Rep 18(4):127133 Venugopal R, Jaiswal AK (1998) Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

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These trials have included different patient classes and comparators, and the results have generally shown positive outcomes in terms of both glycemic control and weight management

This deliberate approach reduces side effects, improves long term tolerance of the medication, and most importantly helps preserve lean muscle mass during weight loss

More options are on the way, including stronger oral formulations that obviate the need for weekly injections