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The trial, published in the New England Journal of Medicine , showed that treatment with the medication resulted in less progression of motor disability than placebo at 12 months, although it was associated with gastrointestinal adverse effects
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10.1007/s13311-020-00968-6 139 SantocchiE.GuiducciL
Gastrointestinal symptoms are the most frequently reported adverse effects, occurring in a substantial proportion of patients
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