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Intragastric and oral administration give detectable plasma levels for several hours in rodent studies, supported by the proline-rich sequence resisting cleavage by gastric proteases
Actin structure and function
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At 9,111 Da with three disulfide bonds (C6-C48, C18-C61, C47-C52) essential for receptor binding, IGF-1 LR3 is a folded protein that can irreversibly denature under conditions that small peptides tolerate easily, including vigorous vortexing, repeated freeze-thaw cycles, room temperature exposure exceeding 30 minutes, and adsorption to untreated plastic surfaces
C.van ErpP
Athletic and Weight Support 13
