Kidney injury has been associated with previous generations of GLP-1 medications, specifically exenatide and liraglutide
Free fatty acids from either adipose tissue (fat), or from the conversion of excess carbohydrate intake, accumulate in the liver cell resulting in oxidative stress, inflammation, and liver injury
Of course there are always exceptionsCalocurb should not be taken by individuals that have any form of gastrointestinal inflammation or inflammatory bowel disease, such as Crohns or ulcerative colitis
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Routine thyroid function monitoring in patients on levothyroxine provides an additional safety net, but there is no requirement for specific thyroid cancer screening in patients without risk factors