What got me here (perimenopause perimenopaus-ing) As estrogen and progesterone fluctuate, and then begin their gradual decline, several metabolic changes occur: Insulin becomes less efficient Estrogen is insulin-sensitizing
doi: 10.1016/j.cophys.2021.01.003 51 HuangYAPereiraERoperSD
102 The GLP-1 RA and Neurogenesis Neurogenesis is a complete process in which neural stem cells (NSCs) proliferate, undergo balanced and imbalanced division to become directed progenitor cells and gradually migrate to functional areas, undergo plasticity changes, and establish synaptic connections with other neurons to generate neural function
262,263 Additionally, substituting dietary SFAs with monounsaturated fatty acids improves nerve function in HFD mice without significantly altering plasma metabolic profiles, suggesting that dietary fats influence neuropathy development
Signals The Brain To Stop Eating (Satiety): GLP-1 crosses the blood-brain barrier and interacts with appetite-regulating receptors in the hypothalamus
To truly improve symptoms, we need to take a whole-person approach looking at both diet and mental health, not just the gut in isolation