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NAC provides the precursors for internal production, while glutathione provides immediate antioxidant activity

Biochemical and Biophysical Research Communications

Nevertheless, their FDA approvals reflect different purposes

Once inside the cell, Fe 3+ is reduced to Fe 2+ via six-transmembrane epithelial antigen of prostate 3 (STEAP3) and transported into the cytosol by divalent metal transporter 1 (DMT1) and ZRT/IRT-like proteins 8 and 14 (ZIP8/14) (Wang et al., 2025d)

Store the reconstituted solution at 2-8C and prepare single-use aliquots at -20C for longer holding

Fibroblast growth factor 2 conjugated superparamagnetic iron oxide nanoparticles (FGF2-SPIONs) ameliorate hepatic stellate cells activation in vitro and acute liver injury in vivo