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By law, Medicare Part D cannot cover drugs prescribed strictly for weight loss, which is why a GLP-1 may be covered for a Medicare patient with type 2 diabetes but not for obesity alone

| 06.01.26 | 8 min read

In db/db mice and advanced glycation end-products (AGEs)-induced HK-2 cells, hyperactivation of the ERK signaling pathway contributes to the impairment of mitophagy flux via regulating TFEB in DKD (117)

A separate product, semaglutide subcutaneous injection (Wegovy), is indicated as an adjunct to lifestyle modifications for weight loss and chronic weight management in obese (BMI 30 kg/m2 or greater) or overweight adults (BMI 27 kg/m2 or greater) with at least 1 weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)

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