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The preservation of nicotinamide substrate drastically increases the efficiency of the NAD+ salvage pathway

This initial period allows the body to adapt to NNMT inhibition while minimizing potential side effects

Individual results may vary

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Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in diet-induced obese mice

It has also been shown to lower homocysteine levels, a molecule linked to inflammation and cognitive decline, with longitudinal studies linking optimal B12 levels with improved cognitive function, mood and reduced risk of neurodegenerative disease