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People taking oral Wegovy (semaglutide) saw a 15% weight-loss average in clinical trials, while those taking Foundayo (orforglipron) lost approximately 12% to 14% of their baseline weight

Gastrointestinal adverse events of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a systematic review and network meta-analysis

Patients should be reassured that this type of hair loss does not typically indicate permanent follicular damage, as noted in Primary Care Dermatology Society (PCDS) guidance on diffuse hair loss

Women of childbearing potential should discuss contraceptive options and pregnancy planning with their prescribing clinician

Suspected adverse drug reactions to retatrutide can be reported through the MHRA Yellow Card scheme at yellowcard

Some small studies have shown promising results in the type 1 diabetes population, especially in those who are overweight and have insulin resistance