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Mast Cell Activation Syndrome Treatment Conventional treatment for mast cell activation syndrome generally involves the use of pharmaceutical and over-the-counter medications to alleviate symptoms, such as the following medications: Epinephrine (such as an EpiPen) for severe reactions First generation H1 blockers diphenhydramine (Benadryl) and hydroxyzine (Vistaril) Second generation H1 blockers, including loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra) H2 blockers, such as ranitidine (Zantac) and famotidine (Pepcid) Aspirin, to block production of prostaglandin D2 and reduce flushing
Different mechanisms create synergy
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Additionally, vitamin B12 is necessary for the metabolism of cells throughout the body, including those involved in energy production and DNA synthesis
This is the documented failure mode on marketplace listings
Some clinicians prefer to use a methylmalonic acid (MMA) test in place of a homocysteine test, but MMA is also a non-specific biomarker
