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What is more, no clear trend for a change in pharmacokinetics was evident across groups with increasing renal dysfunction 12 that allowed us to administer the same dose of the drug and the same blood sampling time points in patients with different degree of renal impairment who were included in our study

Eating smaller, more frequent meals, avoiding high-fat and greasy foods, staying well hydrated, and eating slowly can all help reduce nausea

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Unlike peripheral 5-HT, central 5-HT performs critical control functions in the brain

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