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It is central to: Detoxification: Neutralizing free radicals and heavy metals Immune defense: Maintaining lymphocyte and macrophage function Redox homeostasis: Regulating disulfide bonds and antioxidant recycling Cellular repair: Protecting lipid membranes and mitochondrial DNA Despite its significance, traditional glutathione supplements face major limitations: Poor intestinal absorption Rapid breakdown into constituent amino acids Minimal rise in systemic glutathione levels Weak clinical outcomes This gap between glutathiones potential and its real-world efficacy is what motivated the move toward liposomal delivery systems

It has also been proven crucial in the bodys drug resistance, in particular resistance against anticancer drugs

HZ conceived and directed the idea of the manuscript

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Journal of Acquired Immunodeficiency Syndromes, 53 (3), 311-322

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