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Both formulations contain the same 21-amino acid peptide that binds to GLP-1 receptors with identical mechanism of action

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The differential diagnosis of malignant peripheral nerve sheath tumor from melanoma can also be very challenging, especially as these melanoma variants, particularly desmoplastic/spindle cell melanomas, show no or very little expression of melanocytic markers such as MelanA and HMB45

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The trial randomised adults with obesity who have achieved 5% WL by the end of the 12-week lead-in period (mean WL at the lead-in period was 6.9%) to placebo or tirzepatide