Severe deficiency is a cause of epilepsy: In the 1950s, an unintended experiment showed that when B6 was accidentally left out of infant formula, the babies had seizures
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While L-Carnitine is generally considered safe, excessive consumption may lead to nausea, vomiting, and diarrhea
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Additionally, and Im speculating here, its possible that taking multiple supplements might lead to a buildup of toxic metals in the body: Supplements can contain trace amounts of heavy metals such as lead, mercury, arsenic and cadmium, which are often found in the soil and absorbed by plants
Dec 2013;30(12):1487-1494