doi: 10.1530/JOE-13-0221 24 SeinoYFukushimaMYabeD
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Lidocaine is extensively metabolized in the liver, so drugs that decrease hepatic blood flow (e.g., propranolol) or inhibit CYP1A2/CYP3A4 (e.g., fluvoxamine, ketoconazole, clarithromycin) may elevate systemic concentrations and increase the risk of central nervous system or cardiovascular toxicity
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Biomarkers and Predictors of Adverse Cardiovascular Events in Different Stages of Chronic Kidney Disease
Upon entering into the cells, glucose is converted to glucose-6-phosphate, which in turn triggers the processes of glycolysis and the tricarboxylic acid (TCA) cycle, thereby increasing the levels of cytoplasmic ATP