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ROS cause oxidative damage to various cellular components and disrupt the balance between ECM catabolism and anabolism 119

This case was a wake-up call it established that selling BPC-157 for human use violates the Food, Drug, and Cosmetic Act (FDCA) and can lead to criminal charges

These results were consistent across intraperitoneal and local administration 3

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In other words, in addition to inhibiting the expression of p-STAT3, GHK-Cu likely targets other pathways that inhibit the expression of inflammatory factors