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Why the Myth Persisted The early concern came from animal studies showing ductal hyperplasia and from isolated reports of pancreatitis soon after drug initiation

Individual results vary based on the patients baseline metabolic rate, diet, and physical activity levels

However, it should be noted that growth retardation caused by selenium deficiency may also be associated with the deregulation of bone metabolism 65

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In the Phase 2 trial, retatrutide was given as a once-weekly subcutaneous injection, starting at a low dose and escalating gradually up to 12 mg weekly

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