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[57] AD is associated with an accumulation of DNA damage (double-strand breaks) in vulnerable neuronal and glial cell populations from early stages onward, [58] and DNA double-strand breaks are increased in the hippocampus of AD brains compared to non-AD control brains
Biol Psychiatry 78:702710 Pearce R, Owen A, Daniel S, Jenner P, Marsden C (1997) Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease
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A study of humans with a genetic mutation for CYP2R1, or those done using CYP2R1 knockdown mouse models, demonstrate low circulating levels of 25(OH)VD 3 24
