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Efficacy and safety of the dipeptidyl peptidase-4 inhibitor,sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, doubleblind, non-inferiority trial

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It was conducted in animals under conditions of metabolic stress and cannot be extrapolated to human ADHD

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Here are the differences: Tirzepatide works by activating two key pathways: GLP-1 and GIP