One factor is that Novo Nordisk launched its newly FDA-approved once-daily tablet for semaglutide in January 2026
The odds of achieving 10%, 15%, and 20% or more weight loss were significantly higher with semaglutide (70.9%, 55.6%, and 38.5%, respectively) compared to liraglutide (25.6%, 12.0%, and 6.0%)
3 Another study noted that GLP-1 medications may be more effective when started 74+ months after surgery, possibly because the natural elevation in GLP-1 from surgery begins to wane over time
NAD+ availability may also vary by format and state regulations
In: ObesityWeek 2024, 26 November 2024, San Antonio
Compounded semaglutide is only permitted under limited conditions and is not FDA-approved