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Across the SURPASS trials documented in the Mounjaro FDA prescribing information, injection-site reactions occurred in approximately 3-7% of participants depending on dose, while true systemic allergic responses (hives spreading beyond the site, facial swelling, breathing difficulty) are rare

Mild headaches are common while taking semaglutide and resolve on their own

Katherine Tuttle, executive director for Research Providence Inland Northwest Health in Spokane and one of the substudys lead authors, said

Topical Lotion/Cream: Apply daily to clean, dry skinpreferably after a showerfor full-body coverage

GLP-1 receptor agonists typically increase resting heart rate by 2-4 beats per minute on average, though some patients experience increases of 10 beats per minute or more

Kralj T et al