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4, the three most frequently reported SOC categories were "Gastrointestinal disorders," "General disorders and administration site conditions," and "Investigations." Notably, while "Injury, poisoning, and procedural complications" and "Nervous system disorders" demonstrated higher reporting frequencies compared to other SOCs, these associations did not reach statistical significance in our analysis, suggesting potential reporting bias or confounding factors that warrant further investigation
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Diabetes 2018;67:1773-1782
For example, in 2023, the European Medicines Agency began investigating over 150 reports of suicidal ideation and other psychiatric symptoms linked to GLP-1 receptor agonists, including Ozempic and Wegovy
GLP-1 patches represent an emerging transdermal delivery system designed to administer glucagon-like peptide-1 receptor agonists through the skin, potentially offering an alternative to traditional injections for type 2 diabetes and weight management
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