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These peptides mimic the action of insulin-like growth factor, which plays a crucial role in anabolic muscle cell signaling

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Notably, the treatment preferentially preserved the inner tibial cartilage zone and was associated with a trend toward reduced osteophyte formation [139]

As both H 2 O 2 and BCNU exposure led to excessive cellular GSSG accumulation, their impact on intracellular protein-GSSG adduct formation (protein S -glutathionylation) was subsequently examined in HepG2 cells by western blot analysis using a monoclonal GSSG antibody that specifically binds to GSSG-modified proteins