Genes Dev 2003
Thus, YK-11 exhibits neurotoxic effects, causing damage to the brain
However, the expression of GPx1 has been reported to be down-regulated in thyroid cancer [44], colorectal cancer [45, 46], and gastric cancer [47], whereas GPx1 has been demonstrated to play an oncogenic role in kidney cancer [48], pancreatic cancer [49], and laryngeal squamous cell carcinoma [50]
It is not an FDA-approved generic
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Some people report mild stomach upset or nausea when taking L-carnitine on an empty stomach