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Trientine diHClide is another common copper chelator used for treating Wilson's disease (132), which can selectively bind Cu2+ ions to improve mitochondrial function in patients with hypertrophic cardiomyopathy (73), as well as restore mitochondrial function and normalize myocardial expression and enzymatic activity of proteins involved in energy metabolism among diabetic patients (133)

Here are the groups that are more at risk

National Academies Press

Oral amycretin showed 13.1% weight loss at 12 weeks, offering the possibility of an oral dual GLP-1/amylin agonist

Possible long-term risks of vitamin B12 Most side effects of high doses of B12 are rare and temporary

The mean LVEF was 33.7% and 35.4% in the liraglutide and placebo groups, respectively, and 60% of patients had ischaemic heart disease