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The retina of the eye constitutes an ideal model to study ROS and cellular redox/antioxidant defense systems

Aitken RJ

Intestinal villous M cells: an antigen entry site in the mucosal epithelium

Together, they provide a platform for observing coordinated or independent pathway activity within a unified solution matrix

But here's the detail you should know: not having enough glutathione contributes to oxidative stress, which plays a major role in the mechanisms of complex disorders

GSH is predominantly in its thiol-reduced form inside the cells, except in the lumen of the endoplasmic reticulum where it exists only in its GSSG form (Figures 2, 4)