Prioritise accordingly, and you'll find the timing question resolves itself within the first week of consistent dosing
org/10.1016/S1472-6483(10)61881-0 Costa, M., Canale, D., Filicori, M., D'lddio, S., & Lenzi, A
found that mice fed on diets supplemented with high sugar and fat had elevated plasma TMAO levels, accompanied with increased TNF- levels and decreased IL-10 levels, which led to myocardial fibrosis (98)
However, the long-term treatment with GLP-1RAs may reduce the insulin levels in both T2DM (122) and prediabetic patients (123), owing to the glycemic normalization and increased insulin sensitivity in these patients
Available at: 22 RanganathLRBeetyJMMorganLMWrightJWHowlandRMarksV
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex