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Description

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A published report has shown that the NF-B member, RelB, plays a role in upregulating GPX4 expression and suppressing ferroptosis, thereby increasing the resistance of ER+ breast cancer cells to Tamoxifen [32]

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Thus, unlike WT-Bcr-Abl cells, T315I-Bcr-Abl cells are less vulnerable to JMF4073 in vitro and in vivo

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