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For an additional insight into the mechanism of action, the tumorous tissue was stained with a ROS-specific dye and analyzed by CLSM

Data availability The RNA-seq data used in this study for the human BAT/WAT and pure murine adipocytes transcriptome are available in the European Nucleotide Archive under accession code PRJEB20634

Meanwhile, DIO3 depletes the resources that can be utilized for the production of active thyroid molecules by catalyzing the conversion of T 4 and T 3 into inactive metabolites

Ideally, the injection is administered into a fatty layer of skin, such as: back of arm, abdomen, or flank/lumbar region

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