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However, the thermogenic phenotype and protective effect on diet-induced obesity of AgRP-specific GHS-R knockout mice was less pronounced when compared to that of GHS-R total neuronal knockout mice 9, 35

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Further, it activates muscle stem cells, promoting tissue regeneration, and reverses insulin resistance in relevant animal models, all with good systemic tolerability 1,2

J Fish Dis 2(6):519528 Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase