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Even small amounts of absorbed water can initiate hydrolysis reactions that fragment the peptide chain

While the protocol allowed for complete cessation, many remained on some dose of semaglutide and it is unclear how many stopped entirely

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DMA will request an assessment from the European Pharmacovigilance Risk Assessment Committee (PRAC)

doi: 10.1007/s12035-016-0297-1 50 WaismanALiblauRSBecherB