The regulation of COX2 expression is complex, involving transcriptional and post-transcriptional mechanisms influenced by cytokines, growth factors, and pro-inflammatory stimuli (225)
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However, the hypercoagulable state, as well as the molecular mechanism of this aspect of the pathogenesis of -thalassemia/HbE, remains poorly understood
10.1002/mnfr.201800427 23 HolmanJ
This helps keep products slightly more acidic and compatible with skin's natural pH