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Y1-R-mediated effects on pancreatic islets Our experiments were also designed to determine whether peptides that are efficacious at lower concentrations and/or those that promote modified internalization/-arrestin recruitment might be capable of sustaining the beneficial effects beyond those currently observed while also reducing the frequency of adverse events

McGettrick, A

472,473,474 Integrins are crucial transmembrane receptors that mediate the interaction between cells and the ECM, playing a vital role in cellular signaling and structural integrity

Mitochondrial signalling: MOTS-c is the only compound in the group targeting the AMPK/SIRT3 axis, addressing the metabolic driver of epithelial dysfunction

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Abdel Aziz MT, El-Asmer MF, Mostafa T, Mostafa S, Atta H, Aziz Wassef MA, et al