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However, considering that the safety and tolerability profile of oral semaglutide in PIONEER 12 was consistent with that of the global PIONEER trials and with the safety profile of the GLP-1RA drug class, it is reasonable to assume that long-term safety in this population may be consistent with that seen in the long-term global trials
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Written By: Pharmacally medical News Desk The New England Journal of Medicine has published results from the SURPASS-CVOT trial (NCT04255433), a landmark cardiovascular outcomes study evaluating tirzepatide in people with type 2 diabetes and established atherosclerotic cardiovascular disease
doi: 10.1093/plcell/koac237 43 SmithM
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Patients whose diabetes is being managed with the support of semaglutide (sold as Ozempic) are likely to again encounter issues accessing the medication due to ongoing stock shortages
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