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in SURPASS-CVOT, tirzepatide slowed estimated glomerular filtration rate (eGFR) decline relative to dulaglutide [4], [6]
When combined with the metabolic changes that happen while taking GLP-1 medications, the result can be greater fatigue. Scientific American notes that the only way to prevent muscle loss somewhat while losing weight is to combine exercise (particularly resistance exercise and endurance exercise) with a diet higher in protein
Porch 2002
Due to the activation of the sympathetic system and additional synthesis of growth hormone, the survival rate of neurons increases, improving memory (potentially treating dementia), concentration, and optimizing mood (states of anxiety, depression, or bipolar disorder)
