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Those with visible signs of ageing, such as sagging skin, hyperpigmentation, or dryness, may benefit from introducing copper peptides earlier, especially if they have been exposed to environmental stressors like UV damage or pollution

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However, large-scale cardiovascular (CV) outcomes trials (CVOTs) with DPP-4 inhibitors demonstrated CV safety but did not show a reduction in CV events

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There was also no long-term follow-up to assess if any delayed complications (for example, abnormal tissue growth or tumor formation) occurred after the injection