In a clinical trial, PEA was able to significantly reduce symptoms of GERD, such as heartburn and acid reflux
Additionally, chronic supplementation has shown potential in ameliorating factors associated with metabolic syndrome and cardiovascular disease, such as arterial hypertension and impaired glucose tolerance.[13] A systematic review and meta-analysis further supports these findings, revealing that L-carnitine supplementation at doses of 13 g/day significantly reduced waist circumference, systolic blood pressure, fasting blood sugar, and triglycerides, while also increasing HDL cholesterol
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Some recent research suggests metformin may also negatively impact riboflavin (vitamin B2) status - the authors identified a degree of inverse association between metformin and B2 status
No preservatives, separating agents or binding agents are used in production
GLP1-RA users used GLP1-RA medications for a mean (SD) of 568 (532) days