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Frankel WL, Zhang W, Singh A, et al

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The findings, published in The New England Journal of Medicine , highlight the potential of GLP-1 receptor agonism combined with amylin analog therapy to deliver clinically meaningful weight loss beyond currently available treatments

It is known that peptide 20 potently reversed metabolic disorders in rodent models of obesity and diabetes, characteristic of increased energy expenditure and elevated circulating FGF21 levels as a result of GCGR agonism 22,23